IRIC building in winter
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CMCI Team Wins Interdisciplinary Award

The University Awards for Excellence recognize and encourage excellence in all forms at the academic level. Recently, the 2019 Interdisciplinary Award was presented to the Flow Ventilators Team for their collaborative efforts for working to improve treatments for asthma and other lung diseases. Team members include 4 researchers from 2 colleges: Tao Xing, associate professor…

Tackling Critical Issues in the Ebola Epidemic Through Modeling Viral Evolution

Tackling Critical Issues in the Ebola Epidemic Through Modeling Viral Evolution

Project Team: Marty Ytreberg (PI), Celeste Brown (Co-PI), Craig Miller (Co-PI), Holly Wichman, Tanya Miura, Chris Mirabzadeh, Kyle Martin Ebola surface glycoprotein (blue) bound by antibodies (brown). In dark blue are other known epitopes (antibody binding sites). In orange and red are mutations from the recent epidemic in West Africa. The goal of this project,…

Modeling Variability in Persistence Induced From Within by a Toxic Metabolite
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Modeling Variability in Persistence Induced From Within by a Toxic Metabolite

Project Team: Christopher Marx (PI), Andreas Vasdekis (Co-PI), Chris Remien, Siavash Riazi, Denis Liyu Multidrug antibiotic persistence, which allows some cells that lack genetic resistance to survive antibiotic stresses by becoming dormant, is a major public health concern. This exploratory project will use data from state-of-the-art image cytometry and single-cell analysis in combination with mechanistic mathematical…

IRIC building in winter

Determining the Regulation of Chlamydial Development Through Experimental Modeling

Project Team: Scott Grieshaber (PI), Nicole Grieshaber, Anders Omsland, Christopher Remien Chlamydia are obligate intracellular bacteria that cause a range of diseases in both man an animals. Chlamydia like bacteria infect just about all eukaryotic organisms on the planet, from man to amoeba. All Chlamydiae, including the human pathogens C. trachomatis, C. pneumoniae, and C. psittaci, share a…

Multi-Scale Model of Interactions Between Lung and Pulmonary Ventilation
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Multi-Scale Model of Interactions Between Lung and Pulmonary Ventilation

Project Team: Tao Xing (PI), Gordon Murdoch (Co-PI), Michelle Wiest, Loel Fenwick, Rabijit Dutta Without adequate respiration, life ceases in as little as three minutes. The failure of effective spontaneous respiration requires immediate intervention to preserve life. However, lungs are far more complicated than simple bags at the ends of tubes. Life support or therapeutic…