The Institute for Modeling Collaboration and Innovation hosts Data Carpentries workshops each semester to improve data literacy and reproducible science. The Carpentries teaches foundational computational and data science skills to researchers worldwide. The spring workshop, Genomics in Unix and R, is quickly approaching but there is still space for participants to join. Attendees may register for U of…
Working Group leader: Erich Seamon Group members: Jonathan Barnes, Sarah Bassing, Nurbanu Bursa, Matt Falcy, Jean-Marc Gauthier, Xiao Hu, Jennifer Johnson-Leung, Ginny Lane, Hussain Qazaq, Dilshani Sarathchandra, Terence Soule, Klas Udekwu, James Van Leuven, Meng Zhao, Helen Brown Originated: August 2023 Description: This working group will explore research efforts that connect climate change with health…
Working Group leader: Esteban Hernandez-Vargas, Klas Udekwu Group members: Alejandro Anderson, Matt Kinahan, Ishmael Staples Originated: July 2023 Description: This working group will develop the mathematical foundations to predict antibiotic-resistant and -susceptible bacteria population dynamics. Computational algorithms will indicate the best chronological order and respective duration of each antibiotic.
Join us at 12:00 p.m. for coffee and treats before the presentation. “Outsmarting pathogens with protein engineering: Lessons from pertussis, cytomegalovirus and coronavirus” There is growing interest in development of antibodies to provide instant immunity that protects susceptible individuals against infectious diseases, especially pathogens for which no vaccine is yet available. However, many of these…
Working Group Leader: Bert Baumgaertner Group Members: Florian Justwan, Kendal Mitton, Chenangnon Tovissode Originated: January 2023 Description: This working group uses both modeling and empirical investigations to understand the role that evidentiary standards play when individuals evaluate claims. We are interested in the systematic ways standards of evidence differ across various types of claims (e.g….
Working Group Leader: Tanya Miura. Esteban Vargas, Jean-Marc Gauthier Group members: Pallavia Deol, Eugenia Yeboah, Rodolfo Blanco Rodriguez, Benjamin Whipple Originated: November 8, 2022 Description: The Mathematical Immunology Working Group will develop mathematical models to explain the roles of immune responses during respiratory viral infections.
Working Group Leader: Marty Ytreberg Group Members: Jonathan Barnes, Jagdish Patel, America Chi Originated: December 15, 2022 Description: MoMo will brainstorm ideas to participate in the pandemic preparedness proposal that will be led by University of Texas, Austin.
Title: Using molecular modeling to assess structural conservation of KP4-Like proteins and their potential as antifungals Project Team: Paul Rowley, Jonathan Barnes Start Date: May 2022 KP4 protein has been used as a potent antifungal drug to reduce the spoilage of commodity crops. While the potential of KP4 has not been fully realized due to…
Title: Synergistic mutations allow for antibody resistance in respiratory syncytial virus Project Team: Tanya Miura, Jonathan Barnes Start Date: June 2022 This project was initially funded by the NSF EPSCoR Track II Geno-Pheno Grant to use molecular modeling to predict antibody escape variants of respiratory syncytial virus (RSV). In that work, we identified five novel…
Title: The modeling of the HIV Capsid with novel binding sites on Nucleoporin 153 Project Team: Paul Rowley, Shunji Li, Jagdish Patel Start Date: August 2021 A molecular modeling approach will be used to assess whether homologs of NUP153 motif-1 interact with the HIV-1 capsid. We have preliminary binding data which suggest at least one…