Working Group leader: Tanya Miura & Paul Rowley

Group members: Shunji Li, Angela Crabtree, Sierra Beach, Kevin Hutchinson, Laura Steiner

Originated: August, 2017

Description:

MoVIES is a group designed to bring together the two CMCI-affiliated eukaryotic virology labs at U of I to discuss empirical approaches to test computational predictions of molecular interactions.  The three principle eukaryotic viruses discussed will be Ebolavirus, RSV and HIV.

Our goal is to develop a small community of researchers that will meet to discuss technical and scientific problems pertinent to laboratory experimentation in the context of molecular modeling.  This group will be initially working to setup experimental systems in HIV, Ebolavirus and RSV that are robust and amenable to test computation predictions in line with the goals of the awarded EPSCoR grant.

Publications:

Initiating a watch list for Ebola virus antibody escape mutations

Miller CR, Johnson EL, Burke AZ, Martin KP, Miura TA, Wichman HA, Brown CJ, Ytreberg FM (2016) Initiating a watch list for Ebola virus antibody escape mutations. PeerJ 4:e1674.