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IMCI Invites DAG and MAG Grant Applications

IMCI invites applications for two of our initiatives. Both initiatives support research that involves modeling from any field. Also note that we are hosting a Brown Bag Lunch discussion of DAGs specifically for researchers from CLASS and other colleges that may be unaware of the opportunities we offer – see details below. Anyone who wants to learn more about out Data Access Grants is welcome to attend.

Data Access Grants – DAGs

To enable researchers to generate preliminary data for research grant proposals, IMCI is awarding Data Access Grants (DAGs). These grants do not cover personnel; rather, they cover costs (generally <$4000) to generate needed data. Examples of services and items we will consider include DNA sequencing, ddPCR, cryo-EM, mass spectrometry, reagents for an experiment, data purchase, a pilot survey, or software. We will consider other requests in the range of a few thousand dollars with strong justification related to a specific modeling-based grant proposal. Any area of research that involves modeling will be considered. DAG deadlines will occur 4 times per year.  The next deadline is January 18th, 2022. Review the guidelines for information on how to apply. 

Modeling Access Grants – MAGs

IMCI supports individuals or groups preparing to submit grant proposals within the next year through the Modeling Access Grant (MAG) Program. MAGs do not provide funding but rather expertise in the modeling aspects of a grant proposal, including developing preliminary models for inclusion in the proposal. Any area of research that involves modeling will be considered. Applicants should consult IMCI Associate Director Marty Ytreberg prior to developing a MAG proposal to obtain advice on whether current Collaboratorium resources match the investigator’s needs. MAG proposals are short and will be accepted anytime during the year; the approval process can generally be completed within two weeks of receipt of the final proposal.

IMCI Invites DAG and MAG Grant Applications

IMCI invites applications for two of our initiatives. Both initiatives support research that involves modeling from any field. Also note that we are hosting a Brown Bag Lunch discussion of DAGs specifically for researchers from CLASS and other colleges that may be unaware of the opportunities we offer – see details below. Anyone who wants to learn more about out Data Access Grants is welcome to attend.

Data Access Grants – DAGs

To enable researchers to generate preliminary data for research grant proposals, IMCI is awarding Data Access Grants (DAGs). These grants do not cover personnel; rather, they cover costs (generally <$4000) to generate needed data. Examples of services and items we will consider include DNA sequencing, ddPCR, cryo-EM, mass spectrometry, reagents for an experiment, data purchase, a pilot survey, or software. We will consider other requests in the range of a few thousand dollars with strong justification related to a specific modeling-based grant proposal. Any area of research that involves modeling will be considered. DAG deadlines will occur 4 times per year.  The next deadline is October 12th. Review the guidelines for information on how to apply. 

A Brown Bag Lunch discussing DAGs is scheduled for September 21st at 12:30 by Zoom https://uidaho.zoom.us/j/83682698077.

Modeling Access Grants – MAGs

IMCI supports individuals or groups preparing to submit grant proposals within the next year through the Modeling Access Grant (MAG) Program. MAGs do not provide funding but rather expertise in the modeling aspects of a grant proposal, including developing preliminary models for inclusion in the proposal. Any area of research that involves modeling will be considered. Applicants should consult IMCI Associate Director Marty Ytreberg prior to developing a MAG proposal to obtain advice on whether current Collaboratorium resources match the investigator’s needs. MAG proposals are short and will be accepted anytime during the year; the approval process can generally be completed within two weeks of receipt of the final proposal.

Patel, Colleagues Find Pesticide May Contribute to Global Obesity Epidemic

U of I Molecular Modeler Jagdish Patel worked with Canadian scientists to screen several common food additives or contaminants. They discovered that the commonly sprayed organophosphate insecticide chlorpyrifos puts the break on the burning of calories in the brown adipose tissue of mice and published their work in Nature Communications in August. Slowing down this burning of calories, a process known as diet-induced thermogenesis, causes the body to store these extra calories in the form of white fat, promoting obesity.

Incorporating Bacteriophage into an Experimentally-Tractable Animal Model System

Project Team: James T. Van Leuven, Emma Altman

The microbial communities colonizing animal guts are highly influential to host health and development. Animal hosts are impacted by the species of microbes present and temporal changes in their abundances, but the forces governing these dynamics are poorly understood. Bacteriophages modulate bacterial community composition through predation. They also facilitate horizontal gene transfer, stimulate the immune systems of animals, and can be used to fight antibiotic-resistant bacterial infections. The inclusion of bacteriophages in microbial ecosystem models and testing of these models is critical to understand how these viruses contribute to microbial community dynamics and evolution, and ultimately, to host health.

The goal of the proposed research is to test the molecular, ecological, and evolutionary roles of bacteriophages in host-associated microbial communities using honey bees and their associated gut bacteria. We will modify and apply models of microbial community dynamics to time-series data collected on bee microbiota and then test these models by perturbing bee microbiomes. This project will benefit from collaborative research across institutions and will boost interdepartmental research at University of Idaho.

Drug Discovery

Working Group leader: Marty Ytreberg

Group members: Matthew Bernards, Patrick Hrdlicka, Tanya Miura, Jagdish Patel, Paul Rowley, Soumya Srivastava, Kris Waynant, Holly Wichman, Jonathan Barnes, Suki Li

Originated: February 2021

Description:

We will be brainstorming ideas on how the U of I can build a center that has a focus on drug discovery. Discussion includes possible focus areas, current expertise, gaps in knowledge/expertise and funding mechanisms.