Project Team: Diana Mitchell (PI), Ousseini Isaaka

Start Date: August 1, 2018

For the 19 genes without significant similarity to genes in humans, the following analyses will be performed in order to identify their putative functions:

  1. identify conserved proteins or protein domains
  2. predict protein localization
  3. search for functional domains
  4. predict cellular and functional pathways
  5. synteny analysis for hypothetical proteins.

The team will identify suitable published RNA-seq datasets for zebrafish macrophages to probe for the presence / absence of these nonorthologous transcripts in other macrophage-mediated immune response.

After identifying conserved proteins or protein domains, we will go on to look for species that are known to have regenerative capacity.