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Epistasis

Working Group leader: Dan Weinreich

Group members: Tanya Miura, Andreas Vasdekis, Brenda Rubenstein, Craig Miller, David Morgan, Jagdish Patel, JT VanLeuven, Jonathan Barnes, Kyle Martin, Marty Ytreberg, Paul Rowley

Originated: November, 2018

Description:

This working group is interested in empirical and theoretical approaches for understanding epistasis and its evolutionary consequences.

EPSCoR Track-2 Genome to Phenome (GenoPheno)

Working Group leader: Marty Ytreberg

Group members: Andreas Vasdekis, Craig Miller, Tanya Miura, Paul Rowley, Holly Wichman, Chris Marx, Jagdish Patel, JT Van Leuven, Jean-Marc Gauthier, Brian Clevely, Brenda Rubenstein, Dan Weinreich, Mandar Naik, Brent Lockwood, Melissa Pespeni

Originated: October 2018

Description:

The purpose of this working group is to discuss issues that are potentially important to all 50ish members of the EPSCoR Track-2 project. The goal of this group is to meet approximately bi-weekly during the academic year to discuss relevant topics to the project, e.g., publishing, grantsmanship, reporting, etc.

The full group met together for the first time in June, 2018.

Director’s Message October 2018

Director’s Message October 2018

Dear Friends & Colleagues,

There are so many good things happening within CMCI! I want to bring your attention to an action item and share a few recent accomplishments.


ACTION ITEM: REPORTING

It’s reporting season! Please respond to Michele’s request for information in a timely manner. We have just a few weeks to get everything put together. Regardless of whether or not you submitted a project proposal through CMCI, we want to know about it. All of what anyone affiliated with CMCI does counts towards effort for reporting purposes. We are missing MANY Working Group Reports.

COBRE RENEWAL

As most of you know, we submitted our 510-page COBRE Renewal proposal in late September. We outlined the following new research projects:

  • Christopher Remien, Population dynamic models of microbial interactions
  • Min Xian, Deep learning for breast ultrasound tumor detection
  • Audrey Fu, Machine learning for identifying causal networks in disease
  • Kyle Harrington, Artificial intelligence for accelerating wound healing
  • Bryn Martin, Computational modeling of cerebrospinal fluid drug delivery

I feel like we submitted a strong proposal. We will have a better idea of the likelihood of renewal after the special study section meets something this spring.

RESEARCH & NEW PROJECTS

Research Project

Modeling Access Grants

Pilot GrantsMatthew Bernards, Determining the Role of Albumin Conformation in Enhanced Bone Repair and Regeneration

Audrey Fu, A Causal Network Approach to Understanding Transcription and Methylation in Breast Cancer

Alan Kolok, Mountain West mine tailings, watersheds and adverse human health outcomes

Externally Awarded Projects

  • Christopher Marx has been awarded a U.S. Department of Energy grant, Using gene editing and an accumulated bioproduct as a reporter for genotypic to phenotypic heterogeneity in growth-vs-production for Methylobacterium extorquens conversion of lignin-derived aromatics to butanol
  • Scott Nuismer will be the University of Idaho PI on a Defense Advanced Research Projects Agency cooperative agreement, Prediction of Spillover Potential and Interventional En Masse Animal Vaccination to Prevent Emerging Pathogen Threats in Current and Future Zones of US Military Operation

THANK YOU for all your contributions, hard work and integrity. We are a great team!

Sincerely,
Holly Wichman
CMCI Director

Reproducibility in Sciences Working Group Highlighted

Reproducibility in Sciences Working Group Highlighted

The CMCI Working Group, Reproducibility in Sciences or SciRep for short, was recently highlighted in the Lewiston Tribune. The group is comprised of a marketer, a philosopher, a statistician and a computer scientist. They are looking for ways to improve traditional research methods by examining an emerging pattern that shows results from many scientific studies can’t be reproduced.

Group leader Berna Devezer is an associate professor of marketing who enjoys thinking about theoretical problems. “Science is not that linear,” says Devezer. “It progresses in a very chaotic manner. You cannot really trace where knowledge came from. It goes through so many different processes.”

Read the entire article here.

Devezer presented her work to university leadership and donors at the IRIC during Homecoming weekend.

Graduate Student Wins Outstanding Poster

The College of Science held its 14th annual Student Research Exposition on Thursday, October 18. There were 44 entries on display representing three categories: Undergraduate Category, Graduate Category and Sigma Xi Scientific Research Society Award. “All of our entries deserve praise,” stated Mark Nielsen, Associate Dean of the College of Science. “We’re very proud of the quality of student research that was on display.”

CMCI student researcher Emmanuel Ijezie‘s poster, “Rhinovirus curtails disease severity in respiratory viral co-infections in mice,” was one of two outstanding posters selected in the Graduate Category. He is majoring in Biology and his faculty mentor is Tanya Miura.

Congratulations!